The double marker test, typically conducted in the first trimester (usually between 11 to 14 weeks), is important for several reasons:
Screening for Down Syndrome: The test measures specific proteins (PAPP-A and free β-hCG) in the mother’s blood to assess the risk of chromosomal abnormalities, particularly Down syndrome (trisomy 21).
Assessment of Other Anomalies: Besides Down syndrome, the test can also help identify the risk of other conditions, like trisomy 18.
Early Detection: Identifying risks early allows for further diagnostic testing (like amniocentesis or chorionic villus sampling) if necessary, enabling informed decision-making.
Monitoring Fetal Health: Abnormal results can indicate potential issues that may require closer monitoring throughout the pregnancy.
Peace of Mind: For many expectant parents, knowing their risk can provide reassurance or allow for early planning and intervention if needed.